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Medications That Cause Heat Intolerance or Sun Sensitivity

Some medications can increase your risk of heat intolerance or sun sensitivity, especially during the summer months. Learn which medications to watch out for and how to stay safe in the heat with helpful tips from your local Realo pharmacist.

Understanding Heat Sensitivity and Sun Exposure Risks

In peak summer heat, most of us are thinking about cookouts, beach days, and staying cool. But did you know that hot weather can bring added risks, like heat intolerance and increased sun sensitivity, to taking certain prescription or over-the-counter medications?

At Realo Drugs, we care beyond your prescription. The medications you take are just a small piece of the puzzle to your overall health. That’s why we want to share some important information about your health regimen that can potentially make you more vulnerable to heat-related side effects, and how you can protect yourself and your loved ones in the heat.

What Is Heat Intolerance? What Is Sun Sensitivity?

Heat intolerance occurs when your body has trouble regulating its internal temperature. This could mean sweating less, overheating more easily, or feeling dizzy and weak on warmer days.

Sun sensitivity, also known as photosensitivity, is when your skin becomes more prone to burning or reacting negatively to sunlight—even after just a short period of sun exposure.

Some medications can trigger one or both of these side effects, especially during the hotter, sunnier summer months. If you’re taking any of the medications listed below, it’s a good idea to talk with your pharmacist about how to stay safe in the heat.

8 Common Medications That May Increase Your Risk Of Heat Intolerance or Sun Sensitivity

Not all medications have these side effects. Here are some commonly used ones that may impact your body’s ability to tolerate heat or sun exposure:


Medications That May Cause Heat Intolerance

  1. Diuretics
    These medications help remove excess fluid from the body but can lead to dehydration. This may increase the risk of overheating.
  2. Antihistamines 
    Often used for allergies or sleep, these medications can reduce your ability to sweat, making it harder for your body to cool down.
  3. Antipsychotics
    These medications can interfere with internal temperature regulation, increasing the risk for heat-related illnesses.
  4. Beta-blockers
    Used for blood pressure or heart issues, beta-blockers may slow blood flow to the skin, limiting your body’s ability to release heat.


Medications That May Increase Sun Sensitivity

  1. Antibiotics
    Some antibiotics can make your skin more sensitive to UV rays, increasing your chances of sunburn or rashes.

  2. NSAIDs
    These common pain relievers may cause photosensitivity, especially if used frequently.

  3. Retinoids
    Used to treat acne or skin conditions, retinoids can thin the skin and make it more prone to burning.
  4. Certain Diabetes Medications
    Some medications used to manage blood sugar can increase your skin’s sensitivity to sunlight.

Not sure if your medication increases sun or heat sensitivity? Stop by your nearest Realo Drugs location to ask your local pharmacist.

How to Stay Safe This Summer

You don’t need to avoid the sun altogether, but if you're taking one of the medications above, here are some ways to reduce your risk:

  • Stay hydrated throughout the day, especially if your medication may cause fluid loss.
  • Wear lightweight, loose-fitting clothing and a wide-brimmed hat.
  • Use sunscreen daily, even on cloudy days—SPF 30 or higher is best.
  • Limit outdoor time during peak sun hours, between 10 a.m. and 4 p.m.
  • Take frequent breaks in air-conditioned spaces or shaded areas.
  • Listen to your body. If you start to feel overheated, dizzy, or fatigued, take it seriously.

Looking for more ways to support your wellness at home? Learn more about the services and programs Realo Drugs has to offer.

When to Call Your Pharmacist or Doctor

If you’re feeling unusually tired, lightheaded, flushed in the heat, or notice an unusual rash or sunburn after brief sun exposure, check in with your healthcare provider.

Remember to never stop taking a prescribed medication without first receiving medical guidance. If you're unsure how your medications might interact with summer weather, or are thinking about stopping or switching medications because of the heat’s effects, your Realo pharmacist is here to help.

We Can Beat the Heat, Together

At Realo Drugs, we’re more than just your pharmacy—we’re your neighbors! And we’re here to help you stay well, stay safe, and enjoy the season with confidence.

If you have questions about your medications and heat sensitivity, stop by your local Realo Drugs or give us a call. We’ll walk through your current prescriptions and make sure you have the tools and information you need to stay healthy all summer long.

Find your nearest Realo location or connect with our team today.